BDBM35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine

SMILES CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12

InChI Key InChIKey=HDOZVRUNCMBHFH-UHFFFAOYSA-N

Data  84 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 35255   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  0.5nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity towards human serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  0.910nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  2.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35255(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed